NAD+ 1000mg

NAD+ (Nicotinamide Adenine Dinucleotide)

What is NAD+?

NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in all living cells, playing a key role in energy production, DNA repair, and cellular longevity. It is essential for mitochondrial function, making it a cornerstone of anti-aging, metabolic health, and cognitive performance.

As we age, NAD+ levels naturally decline, leading to fatigue, cellular damage, metabolic dysfunction, and age-related diseases. Supplementing with NAD+ or its precursors (like NMN or NR) can help restore youthful energy levels and enhance overall health.

How It Works (Mechanism of Action)

NAD+ functions as a coenzyme for various metabolic reactions, particularly those related to mitochondrial energy production and cellular repair:

1. Boosts Mitochondrial Energy Production:

   • Increases ATP levels by fueling the Krebs cycle and electron transport chain.

2. Enhances DNA Repair & Cellular Health:

   • Activates sirtuins (SIRT1, SIRT3, SIRT6), which protect DNA and promote longevity.

3. Supports Brain Function & Cognitive Health:

   • Helps combat neurodegeneration by improving brain energy metabolism and reducing oxidative stress.

4. Regulates Metabolic Function & Fat Loss:

   • Increases insulin sensitivity and fat oxidation, making it beneficial for weight management.

5. Reduces Inflammation & Supports Recovery:

   • Lowers chronic inflammation and oxidative stress, leading to improved tissue healing and recovery.

Potential Benefits & Use Cases

• Increased Energy & Reduced Fatigue: Boosts ATP production and fights age-related tiredness.
• Enhanced Cognitive Function & Memory: Improves focus, mental clarity, and neuroprotection.
• Longevity & Anti-Aging: Activates sirtuins, promoting cellular repair and extended lifespan.
• Improved Metabolic Health: Regulates glucose metabolism and insulin sensitivity.
• Faster Recovery & Reduced Inflammation: Helps in muscle recovery, joint repair, and tissue regeneration.

Typical Dosage & Administration

• Administration:
  • IV Therapy: Most effective but requires medical supervision.
  • Subcutaneous or Intramuscular Injection: Used for systemic benefits.
  • Oral Precursors (NMN, NR): Converts into NAD+ inside the body.
• Dosage:
  • IV Drip: 250 mg – 1000 mg per session (used for fatigue, anti-aging, and cognitive enhancement).
  • Injection: 100 mg – 500 mg per injection (daily or every few days).
  • Oral Supplementation: 250 mg – 1000 mg of NMN or NR daily for steady NAD+ replenishment.

Possible Side Effects

• Mild Nausea or Digestive Issues: More common with high doses.
• Flushing & Warmth Sensation: Due to increased metabolism and vasodilation.
• Temporary Fatigue or Brain Fog: Occurs as cells adjust to increased energy production.

Other Relevant Details

• Often stacked with Resveratrol, NMN, or Sirtuin Activators for enhanced longevity effects.
• NAD+ injections and IV therapy are widely used in biohacking, anti-aging medicine, and athletic recovery programs.
• Research is ongoing into its effects on neurodegenerative diseases, muscle preservation, and immune function.