Ipamorelin
What is Ipamorelin?
Ipamorelin is a selective growth hormone secretagogue (GHS) that stimulates natural growth hormone (GH) release without significantly affecting other hormones like cortisol or prolactin. It is considered one of the safest GH-releasing peptides (GHRPs), making it popular in anti-aging, muscle growth, fat loss, and recovery treatments.
Unlike older GH secretagogues such as GHRP-6 and GHRP-2, Ipamorelin provides a clean, controlled GH increase without excessive hunger stimulation or stress hormone elevation.
How It Works (Mechanism of Action)
Ipamorelin mimics ghrelin, the body’s natural hunger hormone, to stimulate the pituitary gland and increase GH production. This leads to:
-
Pulsatile GH Release:
- Promotes a natural, rhythmic GH secretion pattern, avoiding over-saturation or receptor desensitization.
-
No Cortisol or Prolactin Elevation:
- Unlike other GHRPs, Ipamorelin does NOT increase stress hormones, making it safer for long-term use.
-
Fat Loss & Metabolism Boost:
- Enhances lipolysis (fat breakdown) while preserving lean muscle mass.
-
Muscle Growth & Recovery:
- Increases IGF-1 levels, leading to improved muscle repair, collagen synthesis, and overall tissue regeneration.
-
Improved Sleep & Cognitive Function:
- Supports deeper REM sleep, which is crucial for memory, learning, and overall brain health.
Potential Benefits & Use Cases
- Muscle Growth & Strength: Boosts lean muscle mass and protein synthesis.
- Fat Loss & Body Composition Improvement: Enhances metabolic rate and fat oxidation.
- Faster Recovery from Injuries: Supports tendon, ligament, and cartilage repair.
- Anti-Aging & Longevity Benefits: Improves skin elasticity, bone density, and joint health.
- Better Sleep & Energy Levels: Leads to higher-quality sleep and increased daytime energy.
- No Unwanted Side Effects (Like Hunger Stimulation): Unlike GHRP-6, Ipamorelin does NOT cause excessive hunger.
Typical Dosage & Administration
- Administration: Subcutaneous or intramuscular injection.
- Dosage:
- 100 mcg – 300 mcg per injection, taken 2-3 times daily.
- Often used before bed or post-workout to maximize GH pulses.
- Commonly stacked with CJC-1295 (DAC or No-DAC) for sustained GH elevation.
Possible Side Effects
- Mild Water Retention: Temporary bloating due to increased IGF-1 levels.
- Injection Site Reactions: Minor redness or irritation at the injection site.
- Temporary Lightheadedness: Some users experience mild dizziness after injection.
Other Relevant Details
- One of the safest GH-releasing peptides, making it ideal for long-term use.
- Often stacked with CJC-1295, BPC-157, or Thymosin Beta-4 for enhanced recovery and anti-aging effects.
- Does NOT suppress natural GH production, unlike synthetic HGH injections.
Reviews
There are no reviews yet.