GHK-Cu (Copper Peptide)
What is GHK-Cu?
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper Peptide) is a naturally occurring tripeptide that binds to copper ions and plays a vital role in wound healing, tissue regeneration, and anti-aging. It is widely used in skincare, hair restoration, and regenerative medicine due to its ability to stimulate collagen production, repair DNA, and reduce inflammation.
GHK-Cu levels naturally decline with age, leading to slower tissue repair, skin aging, and decreased hair growth. Supplementing with GHK-Cu can help reverse these effects by promoting cellular regeneration and antioxidant protection.
How It Works (Mechanism of Action)
GHK-Cu exerts its benefits through multiple pathways:
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Collagen & Elastin Production:
- Increases type I and III collagen, improving skin elasticity and reducing wrinkles.
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Wound Healing & Tissue Repair:
- Enhances angiogenesis (new blood vessel formation), leading to faster healing of wounds, burns, and scars.
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Anti-Inflammatory & Antioxidant Effects:
- Reduces oxidative stress and inflammation, protecting cells from damage.
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Hair Growth & Follicle Regeneration:
- Stimulates hair follicle stem cells, promoting thicker and healthier hair growth.
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DNA & Stem Cell Repair:
- Activates gene expression for tissue repair, slowing aging and improving overall skin health.
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Muscle & Joint Recovery:
- Assists in tendon, ligament, and cartilage healing, making it beneficial for injuries and joint conditions.
Potential Benefits & Use Cases
- Skin Rejuvenation & Anti-Aging: Reduces wrinkles, fine lines, and hyperpigmentation while improving skin tone.
- Hair Growth Stimulation: Supports hair regrowth in individuals with hair thinning or androgenic alopecia.
- Faster Wound Healing & Scar Reduction: Enhances recovery from cuts, burns, and post-surgical scars.
- Anti-Inflammatory Effects: Helps reduce redness, irritation, and inflammation in skin conditions like eczema and psoriasis.
- Joint & Tendon Repair: Supports cartilage regeneration and recovery from injuries.
Typical Dosage & Administration
- Administration:
- Topical Application: Common in serums, creams, and hair products.
- Subcutaneous Injection: Used for systemic anti-aging and wound healing benefits.
- Dosage:
- Topical Use: 0.05% – 0.5% concentration in serums or creams.
- Injectable Use: 100 mcg – 200 mcg per injection, taken once or twice daily for systemic effects.
Possible Side Effects
- Mild Skin Irritation: Rare cases of redness or itching when applied topically.
- Temporary Fatigue or Dizziness: When injected, some users report mild fatigue.
- Metal Sensitivity: Individuals with copper sensitivity should use with caution.
Other Relevant Details
- GHK-Cu is widely used in the cosmetic industry for its skin regeneration and anti-aging properties.
- Often stacked with BPC-157 and Thymosin Beta-4 for wound healing and tissue repair.
- Highly studied for its gene-regulating properties, making it a promising longevity peptide.
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