What is AOD-9604?
AOD-9604 (Advanced Obesity Drug) is a modified fragment of human growth hormone (HGH) that specifically targets fat loss without the muscle growth effects associated with full HGH. It is a synthetic peptide derived from the 176-191 sequence of HGH, which is responsible for lipolysis (fat breakdown) and inhibition of lipogenesis (fat storage).
AOD-9604 is used primarily for weight loss, metabolism enhancement, and potential joint healing properties. Unlike traditional HGH, it does not cause insulin resistance or affect IGF-1 levels, making it safer for long-term use.
How It Works (Mechanism of Action)
AOD-9604 works by mimicking the natural fat-burning properties of HGH while avoiding unwanted side effects. Its primary mechanisms include:
- Stimulating Lipolysis: Increases the breakdown of stored fat into energy, leading to reduced fat deposits.
- Inhibiting Lipogenesis: Prevents the formation of new fat cells, particularly in stubborn areas like the abdomen.
- Enhancing Metabolism: Helps improve metabolic function, increasing energy expenditure even at rest.
- Potential Cartilage & Joint Repair: Early studies suggest that AOD-9604 may also aid in cartilage regeneration and injury healing, though more research is needed.
Potential Benefits & Use Cases
- Fat Loss & Weight Management: Helps reduce body fat, especially in individuals struggling with obesity.
- Increased Energy & Metabolism: Promotes higher energy levels by accelerating fat oxidation.
- No Impact on Blood Sugar or IGF-1 Levels: Unlike HGH, it does not cause insulin resistance or abnormal growth.
- Potential Joint & Cartilage Healing: Some evidence suggests it may assist in cartilage repair and joint health.
- Cellulite Reduction: May help improve skin elasticity and reduce the appearance of cellulite.
Typical Dosage & Administration
- Administration: Subcutaneous injection (usually in the abdominal area).
- Dosage:
- Standard fat loss protocol: 250 mcg – 500 mcg per day.
- Higher doses (up to 1 mg/day) have been used in clinical studies without adverse effects.
- Often taken in the morning or before exercise for enhanced fat-burning effects.
Possible Side Effects
- Mild Injection Site Irritation: Redness, swelling, or itching at the injection site.
- Temporary Fatigue or Lethargy: Some users experience mild tiredness during the first few days.
- Possible Nausea: Rare but reported in some individuals.
Other Relevant Details
- AOD-9604 has been studied for obesity treatment and has shown promising results in clinical trials.
- It is not regulated as a controlled substance, making it a more accessible fat-loss peptide than HGH.
- Can be stacked with other peptides, such as Ipamorelin or CJC-1295, for enhanced fat-burning and muscle retention effects.
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