MOTS-c

What is MOTS-c?

MOTS-c (Mitochondrial-Derived Peptide) is a small peptide naturally produced by mitochondria that plays a crucial role in energy metabolism, insulin sensitivity, and longevity. It has been extensively studied for its anti-aging, metabolic, and performance-enhancing benefits.

MOTS-c is unique because it regulates cellular metabolism by mimicking the effects of exercise at the molecular level, making it a powerful tool for fat loss, endurance enhancement, and mitochondrial health.

How It Works (Mechanism of Action)

MOTS-c works by activating AMPK (adenosine monophosphate-activated protein kinase), a key energy regulator that influences fat burning, glucose metabolism, and muscle endurance:

Enhances Mitochondrial Function & Energy Production:
- Increases ATP production, improving overall cellular energy efficiency.
Improves Insulin Sensitivity & Glucose Utilization:
- Helps regulate blood sugar levels and reduces insulin resistance, making it beneficial for type 2 diabetes and metabolic syndrome.
Promotes Fat Loss & Lean Muscle Growth:
- Encourages fat oxidation while preserving lean muscle mass.
Mimics the Effects of Exercise:
- Activates genes associated with physical endurance and longevity, even in the absence of exercise.
Supports Longevity & Anti-Aging Benefits:
- Protects against age-related decline by maintaining mitochondrial efficiency and cellular health.

Potential Benefits & Use Cases

Improved Metabolic Health: Increases fat-burning capacity and insulin sensitivity.
Enhanced Physical Endurance & Performance: Improves stamina, muscle function, and recovery.
Anti-Aging & Longevity Effects: Supports mitochondrial function and protects against age-related decline.
Weight Loss & Fat Reduction: Encourages fat loss without muscle degradation.
Diabetes & Blood Sugar Regulation: Helps control glucose metabolism and reduce insulin resistance.

Typical Dosage & Administration

Administration: Subcutaneous injection.
Dosage:
- 5 mg – 10 mg per week, split into daily doses of 5 mg every other day or 2.5 mg daily.
- Can be used in cycles of 4-6 weeks for optimal benefits.

Possible Side Effects

Mild Fatigue or Lethargy: Some users report temporary tiredness after administration.
Temporary Flushing or Warmth: Due to increased cellular activity.
Injection Site Reactions: Minor irritation or redness.

Other Relevant Details

Often combined with other longevity peptides like NAD+, BPC-157, and Epitalon.
Considered a potential anti-aging breakthrough due to its ability to mimic exercise at the cellular level.
Being researched for its effects on muscle loss prevention, cognitive function, and mitochondrial disorders.